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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004457

Entrez Gene ID

6554

Official Gene Symbol

SLC10A1

Synonyms

NTCP

Gene name

solute carrier family 10 (sodium/bile acid cotransporter family), member 1

Gene Type

protein-coding

Chromosome

14

Genomics Location

14q24.1

Known cancer genes

Yes

Protein products

cDNA, FLJ94688, highly similar to Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10

Sodium/bile acid cotransporter

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:10905
MIM:182396
Ensembl:ENSG00000100652
HPRD:01672
RefSeq Genomic nucleotide accession:AC_000057
RefSeq Genomic nucleotide gi:89161192

Liver relevance

Liver sepcificity

Yes/No

Yes

Evidence

Translational level from literatures

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006810

transport

GO:0006811

ion transport

GO:0006814

sodium ion transport

GO:0008206

bile acid metabolic process

GO:0008508

bile acid:sodium symporter activity

GO:0015293

symporter activity

GO:0015711

organic anion transport

GO:0015721

bile acid and bile salt transport

GO:0016323

basolateral plasma membrane