HuLG004460

Entrez Gene ID

6557

Official Gene Symbol

SLC12A1

Synonyms

BSC1|MGC48843|NKCC2

Gene name

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q15-q21.1

Known cancer genes

Yes

Protein products

cDNA FLJ58996, highly similar to Solute carrier family 12 member 1

Uncharacterized protein

SLC12A1 protein

Solute carrier family 12 member 1

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:10910
MIM:600839
Ensembl:ENSG00000074803
HPRD:02908
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

GO annotation

GO:0001822

kidney development

GO:0005215

transporter activity

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0006810

transport

GO:0006811

ion transport

GO:0006813

potassium ion transport

GO:0006814

sodium ion transport

GO:0006821

chloride transport

GO:0007588

excretion

GO:0008511

sodium:potassium:chloride symporter activity

GO:0015293

symporter activity

GO:0016021

integral to membrane

GO:0016324

apical plasma membrane

GO:0034220

ion transmembrane transport

GO:0048878

chemical homeostasis

GO:0055085

transmembrane transport