Gene basic information
| LiverAtlas Gene ID |
HuLG004492 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SMARCA2 |
|
Synonyms |
BAF190|BRM|FLJ36757|MGC74511|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a |
|
Gene name |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
9 |
|
Genomics Location |
9p22.3 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ36757 fis, clone UTERU2018522, highly similar to Human transcriptional activator hSNF2a |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11098
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0000166 |
nucleotide binding |
|
GO:0000790 |
nuclear chromatin |
|
GO:0003677 |
DNA binding |
|
GO:0003713 |
transcription coactivator activity |
|
GO:0004386 |
helicase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005730 |
nucleolus |
|
GO:0006338 |
chromatin remodeling |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
|
GO:0007399 |
nervous system development |
|
GO:0008094 |
DNA-dependent ATPase activity |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0016514 |
SWI/SNF complex |
|
GO:0016818 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
|
GO:0030308 |
negative regulation of cell growth |
|
GO:0043231 |
intracellular membrane-bounded organelle |
|
GO:0045111 |
intermediate filament cytoskeleton |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0071564 |
npBAF complex |
|
GO:0071565 |
nBAF complex |
|
GO:0071778 |
WINAC complex |
