Gene basic information
| LiverAtlas Gene ID |
HuLG004539 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SOAT1 |
|
Synonyms |
ACACT|ACAT|ACAT1|RP11N215I23.2|SOAT|STAT |
|
Gene name |
sterol O-acyltransferase 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q25 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11177
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000062 |
fatty-acyl-CoA binding |
|
GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
|
GO:0004772 |
sterol O-acyltransferase activity |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005792 |
microsome |
|
GO:0008202 |
steroid metabolic process |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0010742 |
macrophage derived foam cell differentiation |
|
GO:0010878 |
cholesterol storage |
|
GO:0015485 |
cholesterol binding |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0016740 |
transferase activity |
|
GO:0033344 |
cholesterol efflux |
|
GO:0034379 |
very-low-density lipoprotein particle assembly |
|
GO:0034435 |
cholesterol esterification |
|
GO:0034736 |
cholesterol O-acyltransferase activity |
|
GO:0042632 |
cholesterol homeostasis |
|
GO:0042986 |
positive regulation of amyloid precursor protein biosynthetic process |
