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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004546

Entrez Gene ID

6653

Official Gene Symbol

SORL1

Synonyms

C11orf32|FLJ21930|FLJ39258|LR11|LRP9|SORLA|SorLAN1|gp250

Gene name

sortilin-related receptor, L(DLR class) A repeats containing

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q23.2-q24.2

Known cancer genes

Yes

Protein products

Sortilin-related receptor

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11185
MIM:602005
Ensembl:ENSG00000137642
HPRD:03595
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004888

transmembrane receptor activity

GO:0005887

integral to plasma membrane

GO:0006810

transport

GO:0006869

lipid transport

GO:0006898

receptor-mediated endocytosis

GO:0008202

steroid metabolic process

GO:0008203

cholesterol metabolic process

GO:0016020

membrane

GO:0030169

low-density lipoprotein particle binding

GO:0034362

low-density lipoprotein particle