Gene basic information
| LiverAtlas Gene ID |
HuLG004547 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SOS1 |
|
Synonyms |
GF1|GGF1|GINGF|HGF|NS4 |
|
Gene name |
son of sevenless homolog 1 (Drosophila) |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2p21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11187
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003677 |
DNA binding |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005088 |
Ras guanyl-nucleotide exchange factor activity |
|
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
|
GO:0005100 |
Rho GTPase activator activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0007165 |
signal transduction |
|
GO:0007173 |
epidermal growth factor receptor signaling pathway |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0007265 |
Ras protein signal transduction |
|
GO:0007411 |
axon guidance |
|
GO:0007596 |
blood coagulation |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0008543 |
fibroblast growth factor receptor signaling pathway |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0032321 |
positive regulation of Rho GTPase activity |
|
GO:0035023 |
regulation of Rho protein signal transduction |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0050900 |
leukocyte migration |
|
GO:0051056 |
regulation of small GTPase mediated signal transduction |
