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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004560

Entrez Gene ID

6667

Official Gene Symbol

SP1

Gene name

Sp1 transcription factor

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q13.1

Known cancer genes

Yes

Protein products

Pregnancy-specific protein

Transcription factor Sp1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11205
MIM:189906
Ensembl:ENSG00000185591
HPRD:01796
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003677

DNA binding

GO:0003690

double-stranded DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0008022

protein C-terminus binding

GO:0008134

transcription factor binding

GO:0008270

zinc ion binding

GO:0032993

protein-DNA complex

GO:0035035

histone acetyltransferase binding

GO:0042802

identical protein binding

GO:0042803

protein homodimerization activity

GO:0042826

histone deacetylase binding

GO:0043565

sequence-specific DNA binding

GO:0043923

positive regulation by host of viral transcription

GO:0044419

interspecies interaction between organisms

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046872

metal ion binding