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Gene basic information

LiverAtlas Gene ID	HuLG004564
Entrez Gene ID	6672
Official Gene Symbol	SP100
Synonyms	DKFZp686E07254\|FLJ00340\|FLJ34579
Gene name	SP100 nuclear antigen
Gene Type	protein-coding
Chromosome	2
Genomics Location	2q37.1
Known cancer genes	Yes
Protein products	Uncharacterized protein Putative uncharacterized protein SP100 Putative uncharacterized protein DKFZp686E07254 FLJ00340 protein Nuclear autoantigen Sp-100
Related liver disease name	Liver fibrosis and liver cirrhosis Hepatocellular carcinoma Primary biliary cirrhosis
Database cross reference	HGNC:11206 MIM:604585 Ensembl:ENSG00000067066 HPRD:06844 RefSeq Genomic nucleotide accession:AC_000045 RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes	Yes/No	Yes
	Evidence	EHCO
	Quality score

Ontology annotation

GO ID	GO annotation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0003713	transcription coactivator activity
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008134	transcription factor binding
GO:0016605	PML body
GO:0019221	cytokine-mediated signaling pathway
GO:0019900	kinase binding
GO:0019904	protein domain specific binding
GO:0032526	response to retinoic acid
GO:0032897	negative regulation of viral transcription
GO:0034097	response to cytokine stimulus
GO:0034340	response to type I interferon
GO:0034341	response to interferon-gamma
GO:0034399	nuclear periphery
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0043392	negative regulation of DNA binding
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0044419	interspecies interaction between organisms
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0048384	retinoic acid receptor signaling pathway
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051271	negative regulation of cellular component movement
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0060337	type I interferon-mediated signaling pathway
GO:0070087	chromo shadow domain binding