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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004569

Entrez Gene ID

6678

Official Gene Symbol

SPARC

Synonyms

ON

Gene name

secreted protein, acidic, cysteine-rich (osteonectin)

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q31.3-q32

Known cancer genes

Yes

Protein products

Secreted protein, acidic, cysteine-rich (Osteonectin), isoform CRA a

SPARC

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:11219
MIM:182120
Ensembl:ENSG00000113140
HPRD:01631
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001503

ossification

GO:0002576

platelet degranulation

GO:0005509

calcium ion binding

GO:0005515

protein binding

GO:0005518

collagen binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005604

basement membrane

GO:0005615

extracellular space

GO:0007165

signal transduction

GO:0007596

blood coagulation

GO:0030168

platelet activation

GO:0031093

platelet alpha granule lumen

GO:0042127

regulation of cell proliferation

GO:0050840

extracellular matrix binding

GO:0071363

cellular response to growth factor stimulus