Gene basic information
| LiverAtlas Gene ID |
HuLG004570 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SPAST |
|
Synonyms |
ADPSP|FSP2|KIAA1083|SPG4 |
|
Gene name |
spastin |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2p24-p21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Database cross reference |
HGNC:11233
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0001578 |
microtubule bundle formation |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005768 |
endosome |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005815 |
microtubule organizing center |
|
GO:0005819 |
spindle |
|
GO:0005874 |
microtubule |
|
GO:0006888 |
ER to Golgi vesicle-mediated transport |
|
GO:0007049 |
cell cycle |
|
GO:0007109 |
cytokinesis, completion of separation |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007399 |
nervous system development |
|
GO:0008017 |
microtubule binding |
|
GO:0008219 |
cell death |
|
GO:0008568 |
microtubule-severing ATPase activity |
|
GO:0015630 |
microtubule cytoskeleton |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0016787 |
hydrolase activity |
|
GO:0017111 |
nucleoside-triphosphatase activity |
|
GO:0030154 |
cell differentiation |
|
GO:0030496 |
midbody |
|
GO:0034214 |
protein hexamerization |
|
GO:0043014 |
alpha-tubulin binding |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0048487 |
beta-tubulin binding |
|
GO:0051013 |
microtubule severing |
|
GO:0051260 |
protein homooligomerization |
|
GO:0051301 |
cell division |
