Gene basic information
| LiverAtlas Gene ID |
HuLG004602 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
AKR1D1 |
|
Synonyms |
3o5bred|CBAS2|SRD5B1 |
|
Gene name |
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) |
|
Gene Type |
protein-coding |
|
Chromosome |
7 |
|
Genomics Location |
7q32-q33 |
|
Protein products |
3-oxo-5-beta-steroid 4-dehydrogenase cDNA FLJ59278, highly similar to 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) cDNA FLJ50829, highly similar to 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:388
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004033 |
aldo-keto reductase (NADP) activity |
|
GO:0005496 |
steroid binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006699 |
bile acid biosynthetic process |
|
GO:0006707 |
cholesterol catabolic process |
|
GO:0007586 |
digestion |
|
GO:0008206 |
bile acid metabolic process |
|
GO:0008207 |
C21-steroid hormone metabolic process |
|
GO:0008209 |
androgen metabolic process |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0030573 |
bile acid catabolic process |
|
GO:0047568 |
3-oxo-5-beta-steroid 4-dehydrogenase activity |
|
GO:0047787 |
delta4-3-oxosteroid 5beta-reductase activity |
|
GO:0055114 |
oxidation-reduction process |
