Gene basic information
| LiverAtlas Gene ID |
HuLG004605 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SRF |
|
Synonyms |
MCM1 |
|
Gene name |
serum response factor (c-fos serum response element-binding transcription factor) |
|
Gene Type |
protein-coding |
|
Chromosome |
6 |
|
Genomics Location |
6p21.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11291
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000790 |
nuclear chromatin |
|
GO:0001569 |
patterning of blood vessels |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001707 |
mesoderm formation |
|
GO:0001829 |
trophectodermal cell differentiation |
|
GO:0001947 |
heart looping |
|
GO:0002042 |
cell migration involved in sprouting angiogenesis |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0007015 |
actin filament organization |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007369 |
gastrulation |
|
GO:0007507 |
heart development |
|
GO:0008134 |
transcription factor binding |
|
GO:0009636 |
response to toxin |
|
GO:0009725 |
response to hormone stimulus |
|
GO:0010735 |
positive regulation of transcription via serum response element binding |
|
GO:0010736 |
serum response element binding |
|
GO:0030155 |
regulation of cell adhesion |
|
GO:0034097 |
response to cytokine stimulus |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0045597 |
positive regulation of cell differentiation |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0045987 |
positive regulation of smooth muscle contraction |
|
GO:0046716 |
muscle cell homeostasis |
|
GO:0048589 |
developmental growth |
|
GO:0048666 |
neuron development |
|
GO:0051150 |
regulation of smooth muscle cell differentiation |
|
GO:0051491 |
positive regulation of filopodium assembly |
|
GO:0060055 |
angiogenesis involved in wound healing |
|
GO:0060261 |
positive regulation of transcription initiation from RNA polymerase II promoter |
|
GO:0090009 |
primitive streak formation |
|
GO:0090398 |
cellular senescence |
