Gene basic information
| LiverAtlas Gene ID |
HuLG004643 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
STAT2 |
|
Synonyms |
ISGFN3|MGC59816|P113|STAT113 |
|
Gene name |
signal transducer and activator of transcription 2, 113kDa |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q13.3 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ60293, highly similar to Signal transducer and activator of transcription 2 |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:11363
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003677 |
DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0004871 |
signal transducer activity |
|
GO:0005509 |
calcium ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
|
GO:0007259 |
JAK-STAT cascade |
|
GO:0009615 |
response to virus |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0060337 |
type I interferon-mediated signaling pathway |
|
GO:0060338 |
regulation of type I interferon-mediated signaling pathway |
