Gene basic information
| LiverAtlas Gene ID |
HuLG004644 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
STAT3 |
|
Synonyms |
APRF|FLJ20882|HIES|MGC16063 |
|
Gene name |
signal transducer and activator of transcription 3 (acute-phase response factor) |
|
Gene Type |
protein-coding |
|
Chromosome |
17 |
|
Genomics Location |
17q21.31 |
|
Known cancer genes |
Yes |
|
Protein products |
Signal transducer and activator of transcription 3 isoform 2 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11364
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0001659 |
temperature homeostasis |
|
GO:0001754 |
eye photoreceptor cell differentiation |
|
GO:0003677 |
DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003706 |
ligand-regulated transcription factor activity |
|
GO:0004871 |
signal transducer activity |
|
GO:0005509 |
calcium ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
|
GO:0006606 |
protein import into nucleus |
|
GO:0006928 |
cellular component movement |
|
GO:0006953 |
acute-phase response |
|
GO:0007165 |
signal transduction |
|
GO:0007259 |
JAK-STAT cascade |
|
GO:0007399 |
nervous system development |
|
GO:0008134 |
transcription factor binding |
|
GO:0014070 |
response to organic cyclic compound |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0019901 |
protein kinase binding |
|
GO:0019953 |
sexual reproduction |
|
GO:0032355 |
response to estradiol stimulus |
|
GO:0032870 |
cellular response to hormone stimulus |
|
GO:0034097 |
response to cytokine stimulus |
|
GO:0040014 |
regulation of multicellular organism growth |
|
GO:0042493 |
response to drug |
|
GO:0042593 |
glucose homeostasis |
|
GO:0042755 |
eating behavior |
|
GO:0043434 |
response to peptide hormone stimulus |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045471 |
response to ethanol |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046983 |
protein dimerization activity |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0060396 |
growth hormone receptor signaling pathway |
|
GO:0060397 |
JAK-STAT cascade involved in growth hormone signaling pathway |
|
GO:0070102 |
interleukin-6-mediated signaling pathway |
