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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004647

Entrez Gene ID

6777

Official Gene Symbol

STAT5B

Synonyms

STAT5

Gene name

signal transducer and activator of transcription 5B

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q11.2

Known cancer genes

Yes

Protein products

Signal transducer and activator of transcription 5B

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11367
MIM:604260
Ensembl:ENSG00000173757
HPRD:05037
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000255

allantoin metabolic process

GO:0001553

luteinization

GO:0001666

response to hypoxia

GO:0001889

liver development

GO:0003690

double-stranded DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0004871

signal transducer activity

GO:0005509

calcium ion binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006101

citrate metabolic process

GO:0006103

2-oxoglutarate metabolic process

GO:0006105

succinate metabolic process

GO:0006107

oxaloacetate metabolic process

GO:0006351

transcription, DNA-dependent

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0006549

isoleucine metabolic process

GO:0006573

valine metabolic process

GO:0006600

creatine metabolic process

GO:0006631

fatty acid metabolic process

GO:0006953

acute-phase response

GO:0007259

JAK-STAT cascade

GO:0007548

sex differentiation

GO:0007565

female pregnancy

GO:0007595

lactation

GO:0019218

regulation of steroid metabolic process

GO:0019221

cytokine-mediated signaling pathway

GO:0019530

taurine metabolic process

GO:0019915

lipid storage

GO:0030155

regulation of cell adhesion

GO:0030856

regulation of epithelial cell differentiation

GO:0032355

response to estradiol stimulus

GO:0032496

response to lipopolysaccharide

GO:0032819

positive regulation of natural killer cell proliferation

GO:0032825

positive regulation of natural killer cell differentiation

GO:0032870

cellular response to hormone stimulus

GO:0033077

T cell differentiation in thymus

GO:0035259

glucocorticoid receptor binding

GO:0040014

regulation of multicellular organism growth

GO:0040018

positive regulation of multicellular organism growth

GO:0042104

positive regulation of activated T cell proliferation

GO:0042448

progesterone metabolic process

GO:0043029

T cell homeostasis

GO:0043066

negative regulation of apoptosis

GO:0043434

response to peptide hormone stimulus

GO:0043565

sequence-specific DNA binding

GO:0045086

positive regulation of interleukin-2 biosynthetic process

GO:0045471

response to ethanol

GO:0045579

positive regulation of B cell differentiation

GO:0045588

positive regulation of gamma-delta T cell differentiation

GO:0045647

negative regulation of erythrocyte differentiation

GO:0045885

positive regulation of survival gene product expression

GO:0045931

positive regulation of mitotic cell cycle

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0045954

positive regulation of natural killer cell mediated cytotoxicity

GO:0046449

creatinine metabolic process

GO:0046543

development of secondary female sexual characteristics

GO:0046544

development of secondary male sexual characteristics

GO:0048541

Peyer's patch development

GO:0048661

positive regulation of smooth muscle cell proliferation

GO:0050729

positive regulation of inflammatory response

GO:0051272

positive regulation of cellular component movement

GO:0060397

JAK-STAT cascade involved in growth hormone signaling pathway

GO:0070669

response to interleukin-2

GO:0070670

response to interleukin-4

GO:0070672

response to interleukin-15