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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004659

Entrez Gene ID

6790

Official Gene Symbol

AURKA

Synonyms

AIK|ARK1|AURA|AURORA2|BTAK|MGC34538|STK15|STK6|STK7

Gene name

aurora kinase A

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q13

Known cancer genes

Yes

Protein products

Serine/threonine-protein kinase 6

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:11393
MIM:603072
Ensembl:ENSG00000087586
HPRD:04066
HPRD:04352
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000278

mitotic cell cycle

GO:0004672

protein kinase activity

GO:0004674

protein serine/threonine kinase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005819

spindle

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0005876

spindle microtubule

GO:0006468

protein phosphorylation

GO:0007049

cell cycle

GO:0007051

spindle organization

GO:0007067

mitosis

GO:0019901

protein kinase binding

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0031616

spindle pole centrosome

GO:0031625

ubiquitin protein ligase binding

GO:0031647

regulation of protein stability

GO:0032355

response to estradiol stimulus

GO:0048015

phosphatidylinositol-mediated signaling

GO:0048471

perinuclear region of cytoplasm

GO:0051301

cell division