Gene basic information
| LiverAtlas Gene ID |
HuLG004727 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
MAP3K7 |
|
Synonyms |
MEKK7|TAK1|TGF1a |
|
Gene name |
mitogen-activated protein kinase kinase kinase 7 |
|
Gene Type |
protein-coding |
|
Chromosome |
6 |
|
Genomics Location |
6q15 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Database cross reference |
HGNC:6859
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000186 |
activation of MAPKK activity |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0000287 |
magnesium ion binding |
|
GO:0001525 |
angiogenesis |
|
GO:0001841 |
neural tube formation |
|
GO:0002224 |
toll-like receptor signaling pathway |
|
GO:0002726 |
positive regulation of T cell cytokine production |
|
GO:0002755 |
MyD88-dependent toll-like receptor signaling pathway |
|
GO:0002756 |
MyD88-independent toll-like receptor signaling pathway |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004708 |
MAP kinase kinase activity |
|
GO:0004709 |
MAP kinase kinase kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005671 |
Ada2/Gcn5/Ada3 transcription activator complex |
|
GO:0005829 |
cytosol |
|
GO:0007165 |
signal transduction |
|
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
|
GO:0007249 |
I-kappaB kinase/NF-kappaB cascade |
|
GO:0007250 |
activation of NF-kappaB-inducing kinase activity |
|
GO:0007252 |
I-kappaB phosphorylation |
|
GO:0007254 |
JNK cascade |
|
GO:0008063 |
Toll signaling pathway |
|
GO:0008385 |
IkappaB kinase complex |
|
GO:0010008 |
endosome membrane |
|
GO:0032743 |
positive regulation of interleukin-2 production |
|
GO:0034130 |
toll-like receptor 1 signaling pathway |
|
GO:0034134 |
toll-like receptor 2 signaling pathway |
|
GO:0034138 |
toll-like receptor 3 signaling pathway |
|
GO:0034142 |
toll-like receptor 4 signaling pathway |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043507 |
positive regulation of JUN kinase activity |
|
GO:0043966 |
histone H3 acetylation |
|
GO:0045087 |
innate immune response |
|
GO:0046330 |
positive regulation of JNK cascade |
|
GO:0050852 |
T cell receptor signaling pathway |
|
GO:0050870 |
positive regulation of T cell activation |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051403 |
stress-activated MAPK cascade |
