HuLG004731

Entrez Gene ID

6890

Official Gene Symbol

TAP1

Synonyms

ABC17|ABCB2|APT1|D6S114E|FLJ26666|FLJ41500|PSF1|RING4|TAP1|0102N|TAP1N

Gene name

transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

Gene Type

protein-coding

Chromosome

6

Genomics Location

6p21.3

Protein products

TAP1

TAP1

TAP1 protein

TAP1 protein

TAP1 protein

Transporter 1

TAP1

TAP1

TAP1

Antigen peptide transporter 1

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:43
MIM:170260
Ensembl:ENSG00000168394
HPRD:01359
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0000166

nucleotide binding

GO:0001916

positive regulation of T cell mediated cytotoxicity

GO:0005215

transporter activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005739

mitochondrion

GO:0005743

mitochondrial inner membrane

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006952

defense response

GO:0015031

protein transport

GO:0015197

peptide transporter activity

GO:0015421

oligopeptide-transporting ATPase activity

GO:0015833

peptide transport

GO:0016021

integral to membrane

GO:0016887

ATPase activity

GO:0019060

intracellular transport of viral proteins in host cell

GO:0019885

antigen processing and presentation of endogenous peptide antigen via MHC class I

GO:0030176

integral to endoplasmic reticulum membrane

GO:0042270

protection from natural killer cell mediated cytotoxicity

GO:0042288

MHC class I protein binding

GO:0042605

peptide antigen binding

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO:0042803

protein homodimerization activity

GO:0042825

TAP complex

GO:0043531

ADP binding

GO:0044419

interspecies interaction between organisms

GO:0046967

cytosol to ER transport

GO:0046978

TAP1 binding

GO:0046979

TAP2 binding

GO:0046980

tapasin binding

GO:0046982

protein heterodimerization activity

GO:0055085

transmembrane transport