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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004737

Entrez Gene ID

6898

Official Gene Symbol

TAT

Gene name

tyrosine aminotransferase

Gene Type

protein-coding

Chromosome

16

Genomics Location

16q22.1

Known cancer genes

Yes

Protein products

Tyrosine aminotransferase

Tyrosine aminotransferase

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatitis B

Chronic hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:11573
MIM:613018
Ensembl:ENSG00000198650
HPRD:11776
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004838

L-tyrosine:2-oxoglutarate aminotransferase activity

GO:0005575

cellular component

GO:0005739

mitochondrion

GO:0005829

cytosol

GO:0006103

2-oxoglutarate metabolic process

GO:0006536

glutamate metabolic process

GO:0006559

L-phenylalanine catabolic process

GO:0006572

tyrosine catabolic process

GO:0006979

response to oxidative stress

GO:0008483

transaminase activity

GO:0009058

biosynthetic process

GO:0014070

response to organic cyclic compound

GO:0016597

amino acid binding

GO:0016847

1-aminocyclopropane-1-carboxylate synthase activity

GO:0030170

pyridoxal phosphate binding

GO:0034641

cellular nitrogen compound metabolic process

GO:0046689

response to mercury ion

GO:0051384

response to glucocorticoid stimulus