Gene basic information
| LiverAtlas Gene ID |
HuLG004760 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TCF4 |
|
Synonyms |
E2N2|ITF2|MGC149723|MGC149724|PTHS|SEF2|SEF2N1|SEF2N1A|SEF2N1B|bHLHb19 |
|
Gene name |
transcription factor 4 |
|
Gene Type |
protein-coding |
|
Chromosome |
18 |
|
Genomics Location |
18q21.1 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ16304 fis, clone PUAEN2003408, highly similar to TRANSCRIPTION FACTOR 4 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11634
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000978 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding |
|
GO:0001011 |
sequence-specific DNA binding RNA polymerase recruiting transcription factor activity |
|
GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
|
GO:0001087 |
TFIIB-class binding transcription factor activity |
|
GO:0001093 |
TFIIB-class transcription factor binding |
|
GO:0003677 |
DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005667 |
transcription factor complex |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006367 |
transcription initiation from RNA polymerase II promoter |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0065004 |
protein-DNA complex assembly |
|
GO:0070888 |
E-box binding |
