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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004764

Entrez Gene ID

6929

Official Gene Symbol

TCF3

Synonyms

E2A|ITF1|MGC129647|MGC129648|VDIR|bHLHb21

Gene name

transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)

Gene Type

protein-coding

Chromosome

19

Genomics Location

19p13.3

Known cancer genes

Yes

Protein products

TCF3 protein

TCF3 protein

Transcription factor E2-alpha

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11633
MIM:147141
Ensembl:ENSG00000071564
HPRD:00918
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000080

G1 phase of mitotic cell cycle

GO:0000788

nuclear nucleosome

GO:0002326

B cell lineage commitment

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005667

transcription factor complex

GO:0005737

cytoplasm

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0008134

transcription factor binding

GO:0030183

B cell differentiation

GO:0030890

positive regulation of B cell proliferation

GO:0031435

mitogen-activated protein kinase kinase kinase binding

GO:0032496

response to lipopolysaccharide

GO:0033152

immunoglobulin V(D)J recombination

GO:0042493

response to drug

GO:0042692

muscle cell differentiation

GO:0042802

identical protein binding

GO:0042803

protein homodimerization activity

GO:0043234

protein complex

GO:0043425

bHLH transcription factor binding

GO:0043565

sequence-specific DNA binding

GO:0043966

histone H3 acetylation

GO:0043967

histone H4 acetylation

GO:0045787

positive regulation of cell cycle

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046982

protein heterodimerization activity

GO:0050821

protein stabilization

GO:0051149

positive regulation of muscle cell differentiation

GO:0070644

vitamin D response element binding

GO:0070888

E-box binding