Gene basic information
| LiverAtlas Gene ID |
HuLG004767 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ZEB1 |
|
Synonyms |
AREB6|BZP|DELTAEF1|FECD6|MGC133261|NIL2A|PPCD3|TCF8|ZFHEP|ZFHX1A |
|
Gene name |
zinc finger E-box binding homeobox 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10p11.2 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ50696, highly similar to Transcription factor 8 Zinc finger E-box binding homeobox 1 Zinc finger E-box binding homeobox 1 Zinc finger E-box binding homeobox 1 Zinc finger E-box binding homeobox 1 |
|
Database cross reference |
HGNC:11642
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0003682 |
chromatin binding |
|
GO:0003690 |
double-stranded DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003713 |
transcription coactivator activity |
|
GO:0003714 |
transcription corepressor activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005634 |
nucleus |
|
GO:0005667 |
transcription factor complex |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
|
GO:0006955 |
immune response |
|
GO:0007389 |
pattern specification process |
|
GO:0007417 |
central nervous system development |
|
GO:0008134 |
transcription factor binding |
|
GO:0008270 |
zinc ion binding |
|
GO:0008283 |
cell proliferation |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0010464 |
regulation of mesenchymal cell proliferation |
|
GO:0014823 |
response to activity |
|
GO:0017015 |
regulation of transforming growth factor beta receptor signaling pathway |
|
GO:0030857 |
negative regulation of epithelial cell differentiation |
|
GO:0030900 |
forebrain development |
|
GO:0031667 |
response to nutrient levels |
|
GO:0033081 |
regulation of T cell differentiation in thymus |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046872 |
metal ion binding |
|
GO:0048596 |
embryonic camera-type eye morphogenesis |
|
GO:0048598 |
embryonic morphogenesis |
|
GO:0048704 |
embryonic skeletal system morphogenesis |
|
GO:0051150 |
regulation of smooth muscle cell differentiation |
|
GO:0051216 |
cartilage development |
|
GO:0071560 |
cellular response to transforming growth factor beta stimulus |
