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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004797

Entrez Gene ID

6999

Official Gene Symbol

TDO2

Synonyms

TDO|TPH2|TRPO

Gene name

tryptophan 2,3-dioxygenase

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q31-q32

Protein products

Tryptophan 2,3-dioxygenase

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:11708
MIM:191070
Ensembl:ENSG00000151790
HPRD:01847
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004833

tryptophan 2,3-dioxygenase activity

GO:0005625

soluble fraction

GO:0005829

cytosol

GO:0006569

tryptophan catabolic process

GO:0016491

oxidoreductase activity

GO:0016597

amino acid binding

GO:0019441

tryptophan catabolic process to kynurenine

GO:0019442

tryptophan catabolic process to acetyl-CoA

GO:0019825

oxygen binding

GO:0020037

heme binding

GO:0034641

cellular nitrogen compound metabolic process

GO:0046872

metal ion binding