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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004798

Entrez Gene ID

7001

Official Gene Symbol

PRDX2

Synonyms

MGC4104|NKEFB|PRP|PRX2|PRXII|TDPX1|TPX1|TSA

Gene name

peroxiredoxin 2

Gene Type

protein-coding

Chromosome

19

Genomics Location

19p13.2

Protein products

Peroxiredoxin 2, isoform CRA a

Peroxiredoxin 2, isoform CRA d

Peroxiredoxin-2

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:9353
MIM:600538
Ensembl:ENSG00000167815
HPRD:02763
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000187

activation of MAPK activity

GO:0002536

respiratory burst involved in inflammatory response

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0006916

anti-apoptosis

GO:0006979

response to oxidative stress

GO:0008379

thioredoxin peroxidase activity

GO:0010310

regulation of hydrogen peroxide metabolic process

GO:0016209

antioxidant activity

GO:0016491

oxidoreductase activity

GO:0019430

removal of superoxide radicals

GO:0030194

positive regulation of blood coagulation

GO:0031665

negative regulation of lipopolysaccharide-mediated signaling pathway

GO:0032088

negative regulation of NF-kappaB transcription factor activity

GO:0032496

response to lipopolysaccharide

GO:0034599

cellular response to oxidative stress

GO:0042098

T cell proliferation

GO:0042744

hydrogen peroxide catabolic process

GO:0042981

regulation of apoptosis

GO:0045454

cell redox homeostasis

GO:0045581

negative regulation of T cell differentiation

GO:0048538

thymus development

GO:0048872

homeostasis of number of cells