Gene basic information
| LiverAtlas Gene ID |
HuLG004809 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TERF1 |
|
Synonyms |
FLJ41416|PIN2|TRBF1|TRF|TRF1|hTRF1NAS|tNTRF1 |
|
Gene name |
telomeric repeat binding factor (NIMA-interacting) 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8q13 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11728
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000086 |
G2/M transition of mitotic cell cycle |
|
GO:0000723 |
telomere maintenance |
|
GO:0000781 |
chromosome, telomeric region |
|
GO:0000783 |
nuclear telomere cap complex |
|
GO:0001309 |
age-dependent telomere shortening |
|
GO:0003677 |
DNA binding |
|
GO:0003691 |
double-stranded telomeric DNA binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005694 |
chromosome |
|
GO:0005737 |
cytoplasm |
|
GO:0005819 |
spindle |
|
GO:0005856 |
cytoskeleton |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006917 |
induction of apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0007004 |
telomere maintenance via telomerase |
|
GO:0007049 |
cell cycle |
|
GO:0007067 |
mitosis |
|
GO:0007094 |
mitotic cell cycle spindle assembly checkpoint |
|
GO:0008017 |
microtubule binding |
|
GO:0008156 |
negative regulation of DNA replication |
|
GO:0008301 |
DNA bending activity |
|
GO:0008656 |
caspase activator activity |
|
GO:0010521 |
telomerase inhibitor activity |
|
GO:0010834 |
telomere maintenance via telomere shortening |
|
GO:0031116 |
positive regulation of microtubule polymerization |
|
GO:0032211 |
negative regulation of telomere maintenance via telomerase |
|
GO:0032214 |
negative regulation of telomere maintenance via semi-conservative replication |
|
GO:0042162 |
telomeric DNA binding |
|
GO:0042493 |
response to drug |
|
GO:0042802 |
identical protein binding |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0045840 |
positive regulation of mitosis |
|
GO:0045931 |
positive regulation of mitotic cell cycle |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0051260 |
protein homooligomerization |
|
GO:0051301 |
cell division |
|
GO:0051974 |
negative regulation of telomerase activity |
