Gene basic information
| LiverAtlas Gene ID |
HuLG004810 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TERF2 |
|
Synonyms |
TRBF2|TRF2 |
|
Gene name |
telomeric repeat binding factor 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
16 |
|
Genomics Location |
16q22.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11729
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000723 |
telomere maintenance |
|
GO:0000781 |
chromosome, telomeric region |
|
GO:0000783 |
nuclear telomere cap complex |
|
GO:0001309 |
age-dependent telomere shortening |
|
GO:0001673 |
male germ cell nucleus |
|
GO:0001701 |
in utero embryonic development |
|
GO:0003677 |
DNA binding |
|
GO:0003691 |
double-stranded telomeric DNA binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005694 |
chromosome |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005794 |
Golgi apparatus |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0007004 |
telomere maintenance via telomerase |
|
GO:0007049 |
cell cycle |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0010834 |
telomere maintenance via telomere shortening |
|
GO:0016233 |
telomere capping |
|
GO:0030870 |
Mre11 complex |
|
GO:0031627 |
telomeric loop formation |
|
GO:0031848 |
protection from non-homologous end joining at telomere |
|
GO:0032205 |
negative regulation of telomere maintenance |
|
GO:0032206 |
positive regulation of telomere maintenance |
|
GO:0032214 |
negative regulation of telomere maintenance via semi-conservative replication |
|
GO:0042162 |
telomeric DNA binding |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0070198 |
protein localization to chromosome, telomeric region |
|
GO:0090398 |
cellular senescence |
