Gene basic information
LiverAtlas Gene ID |
HuLG004830 |
Entrez Gene ID |
|
Official Gene Symbol |
TFRC |
Synonyms |
CD71|TFR|TFR1|TRFR |
Gene name |
transferrin receptor (p90, CD71) |
Gene Type |
protein-coding |
Chromosome |
3 |
Genomics Location |
3q29 |
Known cancer genes |
Yes |
Protein products |
cDNA FLJ75881, highly similar to Homo sapiens transferrin receptor (p90, CD71) (TFRC), mRNA |
Related liver disease name |
|
Database cross reference |
HGNC:11763
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001666 |
response to hypoxia |
GO:0004872 |
receptor activity |
GO:0004998 |
transferrin receptor activity |
GO:0005576 |
extracellular region |
GO:0005739 |
mitochondrion |
GO:0005768 |
endosome |
GO:0005886 |
plasma membrane |
GO:0005887 |
integral to plasma membrane |
GO:0005905 |
coated pit |
GO:0006508 |
proteolysis |
GO:0006879 |
cellular iron ion homeostasis |
GO:0006897 |
endocytosis |
GO:0006953 |
acute-phase response |
GO:0007568 |
aging |
GO:0007584 |
response to nutrient |
GO:0008233 |
peptidase activity |
GO:0010033 |
response to organic substance |
GO:0010035 |
response to inorganic substance |
GO:0010039 |
response to iron ion |
GO:0010042 |
response to manganese ion |
GO:0016020 |
membrane |
GO:0016023 |
cytoplasmic membrane-bounded vesicle |
GO:0030544 |
Hsp70 protein binding |
GO:0032526 |
response to retinoic acid |
GO:0033572 |
transferrin transport |
GO:0042470 |
melanosome |
GO:0044419 |
interspecies interaction between organisms |
GO:0046688 |
response to copper ion |
GO:0048471 |
perinuclear region of cytoplasm |
GO:0051087 |
chaperone binding |
GO:0055085 |
transmembrane transport |
GO:0070062 |
extracellular vesicular exosome |