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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004832

Entrez Gene ID

7039

Official Gene Symbol

TGFA

Synonyms

TFGA

Gene name

transforming growth factor, alpha

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p13

Known cancer genes

Yes

Protein products

Protransforming growth factor alpha

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:11765
MIM:190170
Ensembl:ENSG00000163235
HPRD:07522
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000187

activation of MAPK activity

GO:0001525

angiogenesis

GO:0001934

positive regulation of protein phosphorylation

GO:0001948

glycoprotein binding

GO:0004708

MAP kinase kinase activity

GO:0004871

signal transducer activity

GO:0005154

epidermal growth factor receptor binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005634

nucleus

GO:0005886

plasma membrane

GO:0006916

anti-apoptosis

GO:0007165

signal transduction

GO:0007173

epidermal growth factor receptor signaling pathway

GO:0008083

growth factor activity

GO:0008283

cell proliferation

GO:0009986

cell surface

GO:0016021

integral to membrane

GO:0042060

wound healing

GO:0042493

response to drug

GO:0043524

negative regulation of neuron apoptosis

GO:0043526

neuroprotection

GO:0045741

positive regulation of epidermal growth factor receptor activity

GO:0045840

positive regulation of mitosis

GO:0048523

negative regulation of cellular process

GO:0050679

positive regulation of epithelial cell proliferation

GO:0051480

cytosolic calcium ion homeostasis

GO:0051781

positive regulation of cell division

GO:0060749

mammary gland alveolus development