Gene basic information
| LiverAtlas Gene ID |
HuLG004835 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TGFB2 |
|
Synonyms |
MGC116892|TGFNbeta2 |
|
Gene name |
transforming growth factor, beta 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q41 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:11768
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000902 |
cell morphogenesis |
|
GO:0001525 |
angiogenesis |
|
GO:0001540 |
beta-amyloid binding |
|
GO:0001654 |
eye development |
|
GO:0001666 |
response to hypoxia |
|
GO:0001837 |
epithelial to mesenchymal transition |
|
GO:0001942 |
hair follicle development |
|
GO:0002576 |
platelet degranulation |
|
GO:0003007 |
heart morphogenesis |
|
GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
|
GO:0005102 |
receptor binding |
|
GO:0005114 |
type II transforming growth factor beta receptor binding |
|
GO:0005125 |
cytokine activity |
|
GO:0005160 |
transforming growth factor beta receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007050 |
cell cycle arrest |
|
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
|
GO:0007184 |
SMAD protein import into nucleus |
|
GO:0007267 |
cell-cell signaling |
|
GO:0007435 |
salivary gland morphogenesis |
|
GO:0007507 |
heart development |
|
GO:0007596 |
blood coagulation |
|
GO:0008083 |
growth factor activity |
|
GO:0008219 |
cell death |
|
GO:0008283 |
cell proliferation |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0008347 |
glial cell migration |
|
GO:0009611 |
response to wounding |
|
GO:0009790 |
embryo development |
|
GO:0010002 |
cardioblast differentiation |
|
GO:0010634 |
positive regulation of epithelial cell migration |
|
GO:0010693 |
negative regulation of alkaline phosphatase activity |
|
GO:0010718 |
positive regulation of epithelial to mesenchymal transition |
|
GO:0010936 |
negative regulation of macrophage cytokine production |
|
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
|
GO:0016477 |
cell migration |
|
GO:0022601 |
menstrual cycle phase |
|
GO:0030097 |
hemopoiesis |
|
GO:0030168 |
platelet activation |
|
GO:0030199 |
collagen fibril organization |
|
GO:0030307 |
positive regulation of cell growth |
|
GO:0030308 |
negative regulation of cell growth |
|
GO:0030424 |
axon |
|
GO:0030593 |
neutrophil chemotaxis |
|
GO:0031012 |
extracellular matrix |
|
GO:0031069 |
hair follicle morphogenesis |
|
GO:0031093 |
platelet alpha granule lumen |
|
GO:0032147 |
activation of protein kinase activity |
|
GO:0032570 |
response to progesterone stimulus |
|
GO:0032874 |
positive regulation of stress-activated MAPK cascade |
|
GO:0032909 |
regulation of transforming growth factor-beta2 production |
|
GO:0033630 |
positive regulation of cell adhesion mediated by integrin |
|
GO:0042060 |
wound healing |
|
GO:0042416 |
dopamine biosynthetic process |
|
GO:0042476 |
odontogenesis |
|
GO:0042637 |
catagen |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043025 |
neuronal cell body |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043525 |
positive regulation of neuron apoptosis |
|
GO:0045216 |
cell-cell junction organization |
|
GO:0045726 |
positive regulation of integrin biosynthetic process |
|
GO:0045778 |
positive regulation of ossification |
|
GO:0045787 |
positive regulation of cell cycle |
|
GO:0045823 |
positive regulation of heart contraction |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0048103 |
somatic stem cell division |
|
GO:0048566 |
embryonic digestive tract development |
|
GO:0048666 |
neuron development |
|
GO:0048699 |
generation of neurons |
|
GO:0050680 |
negative regulation of epithelial cell proliferation |
|
GO:0050714 |
positive regulation of protein secretion |
|
GO:0050777 |
negative regulation of immune response |
|
GO:0050778 |
positive regulation of immune response |
|
GO:0051781 |
positive regulation of cell division |
|
GO:0051795 |
positive regulation of catagen |
|
GO:0051891 |
positive regulation of cardioblast differentiation |
|
GO:0060038 |
cardiac muscle cell proliferation |
|
GO:0060317 |
cardiac epithelial to mesenchymal transition |
|
GO:0060389 |
pathway-restricted SMAD protein phosphorylation |
