HuLG004842

Entrez Gene ID

7049

Official Gene Symbol

TGFBR3

Synonyms

BGCAN|betaglycan

Gene name

transforming growth factor, beta receptor III

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p33-p32

Known cancer genes

Yes

Protein products

cDNA FLJ76846, highly similar to Homo sapiens transforming growth factor, beta receptor III (betaglycan, 300kDa) (TGFBR3), mRNA

Transforming growth factor beta receptor type 3

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Database cross reference

HGNC:11774
MIM:600742
Ensembl:ENSG00000069702
HPRD:02846
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

GO annotation

GO:0001837

epithelial to mesenchymal transition

GO:0001889

liver development

GO:0003007

heart morphogenesis

GO:0005024

transforming growth factor beta receptor activity

GO:0005114

type II transforming growth factor beta receptor binding

GO:0005160

transforming growth factor beta receptor binding

GO:0005515

protein binding

GO:0005539

glycosaminoglycan binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006955

immune response

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0007243

intracellular protein kinase cascade

GO:0008201

heparin binding

GO:0009897

external side of plasma membrane

GO:0009986

cell surface

GO:0015026

coreceptor activity

GO:0016049

cell growth

GO:0016477

cell migration

GO:0030165

PDZ domain binding

GO:0030509

BMP signaling pathway

GO:0032354

response to follicle-stimulating hormone stimulus

GO:0034673

inhibin-betaglycan-ActRII complex

GO:0034695

response to prostaglandin E stimulus

GO:0034699

response to luteinizing hormone stimulus

GO:0043231

intracellular membrane-bounded organelle

GO:0046332

SMAD binding

GO:0050431

transforming growth factor beta binding

GO:0050680

negative regulation of epithelial cell proliferation

GO:0051271

negative regulation of cellular component movement

GO:0055010

ventricular cardiac muscle tissue morphogenesis

GO:0060021

palate development

GO:0060038

cardiac muscle cell proliferation

GO:0060216

definitive hemopoiesis

GO:0060317

cardiac epithelial to mesenchymal transition

GO:0060318

definitive erythrocyte differentiation

GO:0060347

heart trabecula formation

GO:0060389

pathway-restricted SMAD protein phosphorylation

GO:0070123

transforming growth factor beta receptor activity, type III