HuLG004843

Entrez Gene ID

7050

Official Gene Symbol

TGIF1

Synonyms

HPE4|MGC39747|MGC5066|TGIF

Gene name

TGFB-induced factor homeobox 1

Gene Type

protein-coding

Chromosome

18

Genomics Location

18p11.3

Known cancer genes

Yes

Protein products

Uncharacterized protein

TGFB-induced factor (TALE family homeobox), isoform CRA c

Homeobox protein TGIF1

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatitis C

Chronic hepatitis C

Hepatocellular carcinoma

Database cross reference

HGNC:11776
MIM:602630
Ensembl:ENSG00000177426
HPRD:04023
RefSeq Genomic nucleotide accession:AC_000061
RefSeq Genomic nucleotide gi:89161196

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0001843

neural tube closure

GO:0003682

chromatin binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003714

transcription corepressor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0007275

multicellular organismal development

GO:0007368

determination of left/right symmetry

GO:0008285

negative regulation of cell proliferation

GO:0009953

dorsal/ventral pattern formation

GO:0010629

negative regulation of gene expression

GO:0042493

response to drug

GO:0043565

sequence-specific DNA binding

GO:0045666

positive regulation of neuron differentiation

GO:0048146

positive regulation of fibroblast proliferation

GO:0048387

negative regulation of retinoic acid receptor signaling pathway

GO:0060041

retina development in camera-type eye

GO:0070410

co-SMAD binding

GO:0071363

cellular response to growth factor stimulus

GO:0071445

cellular response to protein stimulus