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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004860

Entrez Gene ID

7071

Official Gene Symbol

KLF10

Synonyms

EGRA|TIEG|TIEG1

Gene name

Kruppel-like factor 10

Gene Type

protein-coding

Chromosome

8

Genomics Location

8q22.2

Known cancer genes

Yes

Protein products

Krueppel-like factor 10

Early growth response protein alpha

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11810
MIM:601878
Ensembl:ENSG00000155090
HPRD:03527
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0001501

skeletal system development

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0006917

induction of apoptosis

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0007267

cell-cell signaling

GO:0008270

zinc ion binding

GO:0008283

cell proliferation

GO:0008285

negative regulation of cell proliferation

GO:0046872

metal ion binding