Gene basic information
| LiverAtlas Gene ID |
HuLG004865 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TIMP1 |
|
Synonyms |
CLGI|EPA|EPO|FLJ90373|HCI|TIMP |
|
Gene name |
TIMP metallopeptidase inhibitor 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
0 |
|
Genomics Location |
Xp11.3-p11.23 |
|
Known cancer genes |
Yes |
|
Protein products |
Tissue inhibitor of metalloproteinase 1 TIMP metallopeptidase inhibitor 1 |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:11820
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002576 |
platelet degranulation |
|
GO:0004857 |
enzyme inhibitor activity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005604 |
basement membrane |
|
GO:0007568 |
aging |
|
GO:0007596 |
blood coagulation |
|
GO:0008191 |
metalloendopeptidase inhibitor activity |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0030168 |
platelet activation |
|
GO:0031093 |
platelet alpha granule lumen |
|
GO:0034097 |
response to cytokine stimulus |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043249 |
erythrocyte maturation |
|
GO:0043434 |
response to peptide hormone stimulus |
|
GO:0046872 |
metal ion binding |
|
GO:0051045 |
negative regulation of membrane protein ectodomain proteolysis |
