Gene basic information
LiverAtlas Gene ID |
HuLG004866 |
Entrez Gene ID |
|
Official Gene Symbol |
TIMP2 |
Synonyms |
CSCN21K |
Gene name |
TIMP metallopeptidase inhibitor 2 |
Gene Type |
protein-coding |
Chromosome |
17 |
Genomics Location |
17q25 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
Database cross reference |
HGNC:11821
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0004857 |
enzyme inhibitor activity |
GO:0005178 |
integrin binding |
GO:0005515 |
protein binding |
GO:0005576 |
extracellular region |
GO:0005604 |
basement membrane |
GO:0008047 |
enzyme activator activity |
GO:0008191 |
metalloendopeptidase inhibitor activity |
GO:0008285 |
negative regulation of cell proliferation |
GO:0009986 |
cell surface |
GO:0030814 |
regulation of cAMP metabolic process |
GO:0043408 |
regulation of MAPKKK cascade |
GO:0045664 |
regulation of neuron differentiation |
GO:0046872 |
metal ion binding |