Gene basic information
| LiverAtlas Gene ID |
HuLG004875 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TLE1 |
|
Synonyms |
ESG|ESG1|GRG1 |
|
Gene name |
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
|
Gene Type |
protein-coding |
|
Chromosome |
9 |
|
Genomics Location |
9q21.32 |
|
Known cancer genes |
Yes |
|
Protein products |
Transducin-like enhancer of split 1 (E(Sp1) homolog, Drosophila) Transducin-like enhancer of split 1 (E(Sp1) homolog, Drosophila) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11837
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0003682 |
chromatin binding |
|
GO:0003714 |
transcription corepressor activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005667 |
transcription factor complex |
|
GO:0007165 |
signal transduction |
|
GO:0007275 |
multicellular organismal development |
|
GO:0008134 |
transcription factor binding |
|
GO:0009887 |
organ morphogenesis |
|
GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
