Gene basic information
| LiverAtlas Gene ID |
HuLG004883 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TLR1 |
|
Synonyms |
CD281|DKFZp547I0610|DKFZp564I0682|KIAA0012|MGC104956|MGC126311|MGC126312|TIL|TIL._LPRS5|rsc786 |
|
Gene name |
toll-like receptor 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
4 |
|
Genomics Location |
4p14 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11847
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004872 |
receptor activity |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006954 |
inflammatory response |
|
GO:0006955 |
immune response |
|
GO:0007165 |
signal transduction |
|
GO:0016020 |
membrane |
|
GO:0030670 |
phagocytic vesicle membrane |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0035354 |
Toll-like receptor 1-Toll-like receptor 2 protein complex |
|
GO:0042116 |
macrophage activation |
|
GO:0042495 |
detection of triacyl bacterial lipopeptide |
|
GO:0042535 |
positive regulation of tumor necrosis factor biosynthetic process |
|
GO:0045087 |
innate immune response |
|
GO:0045410 |
positive regulation of interleukin-6 biosynthetic process |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0071727 |
cellular response to triacyl bacterial lipopeptide |
