Gene basic information
LiverAtlas Gene ID |
HuLG004908 |
Entrez Gene ID |
|
Official Gene Symbol |
TNFAIP1 |
Synonyms |
B12|B61|EDP1|MGC2317|hBACURD2 |
Gene name |
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
Gene Type |
protein-coding |
Chromosome |
17 |
Genomics Location |
17q22-q23 |
Protein products |
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 |
Related liver disease name |
|
Database cross reference |
HGNC:11894
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0004842 |
ubiquitin-protein ligase activity |
GO:0005249 |
voltage-gated potassium channel activity |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005730 |
nucleolus |
GO:0005737 |
cytoplasm |
GO:0005768 |
endosome |
GO:0006260 |
DNA replication |
GO:0006813 |
potassium ion transport |
GO:0006915 |
apoptosis |
GO:0006955 |
immune response |
GO:0008076 |
voltage-gated potassium channel complex |
GO:0009790 |
embryo development |
GO:0016020 |
membrane |
GO:0016477 |
cell migration |
GO:0016567 |
protein ubiquitination |
GO:0017049 |
GTP-Rho binding |
GO:0031463 |
Cul3-RING ubiquitin ligase complex |
GO:0035024 |
negative regulation of Rho protein signal transduction |
GO:0043149 |
stress fiber assembly |
GO:0043161 |
proteasomal ubiquitin-dependent protein catabolic process |