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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004908

Entrez Gene ID

7126

Official Gene Symbol

TNFAIP1

Synonyms

B12|B61|EDP1|MGC2317|hBACURD2

Gene name

tumor necrosis factor, alpha-induced protein 1 (endothelial)

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q22-q23

Protein products

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11894
MIM:191161
Ensembl:ENSG00000109079
HPRD:01856
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004842

ubiquitin-protein ligase activity

GO:0005249

voltage-gated potassium channel activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005768

endosome

GO:0006260

DNA replication

GO:0006813

potassium ion transport

GO:0006915

apoptosis

GO:0006955

immune response

GO:0008076

voltage-gated potassium channel complex

GO:0009790

embryo development

GO:0016020

membrane

GO:0016477

cell migration

GO:0016567

protein ubiquitination

GO:0017049

GTP-Rho binding

GO:0031463

Cul3-RING ubiquitin ligase complex

GO:0035024

negative regulation of Rho protein signal transduction

GO:0043149

stress fiber assembly

GO:0043161

proteasomal ubiquitin-dependent protein catabolic process