HuLG004912

Entrez Gene ID

7132

Official Gene Symbol

TNFRSF1A

Synonyms

CD120a|FPF|MGC19588|TBP1|TNFNR|TNFNRNI|TNFNR55|TNFAR|TNFR1|TNFR55|TNFR60|p55|p55NR|p60

Gene name

tumor necrosis factor receptor superfamily, member 1A

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p13.2

Known cancer genes

Yes

Protein products

Tumor necrosis factor receptor superfamily member 1A

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Alcoholic hepatitis

Alcoholic liver disease

Nonalcoholic steatohepatitis

Database cross reference

HGNC:11916
MIM:191190
Ensembl:ENSG00000067182
HPRD:01861
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

GO annotation

GO:0004872

receptor activity

GO:0005031

tumor necrosis factor receptor activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006693

prostaglandin metabolic process

GO:0006915

apoptosis

GO:0006954

inflammatory response

GO:0008624

induction of apoptosis by extracellular signals

GO:0019221

cytokine-mediated signaling pathway

GO:0032403

protein complex binding

GO:0032496

response to lipopolysaccharide

GO:0033209

tumor necrosis factor-mediated signaling pathway

GO:0042742

defense response to bacterium

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0043234

protein complex

GO:0044419

interspecies interaction between organisms

GO:0045121

membrane raft

GO:0045471

response to ethanol

GO:0045766

positive regulation of angiogenesis

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0050729

positive regulation of inflammatory response

GO:0051291

protein heterooligomerization

GO:0071260

cellular response to mechanical stimulus