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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004913

Entrez Gene ID

7133

Official Gene Symbol

TNFRSF1B

Synonyms

CD120b|TBPII|TNFNRNII|TNFNR75|TNFBR|TNFR1B|TNFR2|TNFR80|p75|p75TNFR

Gene name

tumor necrosis factor receptor superfamily, member 1B

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36.22

Known cancer genes

Yes

Protein products

Tumor necrosis factor receptor superfamily member 1B

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Alcoholic hepatitis

Hepatocellular carcinoma

Alcoholic liver disease

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:11917
MIM:191191
Ensembl:ENSG00000028137
HPRD:01862
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004872

receptor activity

GO:0005031

tumor necrosis factor receptor activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0006915

apoptosis

GO:0006955

immune response

GO:0007166

cell surface receptor linked signaling pathway

GO:0008219

cell death

GO:0016021

integral to membrane

GO:0033209

tumor necrosis factor-mediated signaling pathway

GO:0045121

membrane raft

GO:0050728

negative regulation of inflammatory response

GO:0050779

RNA destabilization