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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004933

Entrez Gene ID

7159

Official Gene Symbol

TP53BP2

Synonyms

53BP2|ASPP2|BBP|P53BP2|PPP1R13A

Gene name

tumor protein p53 binding protein, 2

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q42.1

Known cancer genes

Yes

Protein products

Apoptosis-stimulating of p53 protein 2

cDNA FLJ61231, highly similar to Apoptosis-stimulating of p53 protein 2

TP53BP2 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12000
MIM:602143
Ensembl:ENSG00000143514
HPRD:11803
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005070

SH3/SH2 adaptor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0006915

apoptosis

GO:0006917

induction of apoptosis

GO:0007165

signal transduction

GO:0007417

central nervous system development

GO:0007507

heart development

GO:0009792

embryo development ending in birth or egg hatching

GO:0010212

response to ionizing radiation

GO:0017124

SH3 domain binding

GO:0045786

negative regulation of cell cycle

GO:0048471

perinuclear region of cytoplasm

GO:0051059

NF-kappaB binding