Gene basic information
| LiverAtlas Gene ID |
HuLG004941 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TPM1 |
|
Synonyms |
C15orf13|CMD1Y|CMH3|HTMNalpha|TMSA |
|
Gene name |
tropomyosin 1 (alpha) |
|
Gene Type |
protein-coding |
|
Chromosome |
15 |
|
Genomics Location |
15q22.1 |
|
Known cancer genes |
Yes |
|
Protein products |
Tropomyosin 1 (Alpha) isoform 5 Tropomyosin 1 (Alpha) isoform 3 Tropomyosin 1 (Alpha) isoform 1 Tropomyosin 1 (Alpha) isoform 4 Tropomyosin 1 (Alpha) isoform 6 Tropomyosin 1 (Alpha) isoform 7 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:12010
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001725 |
stress fiber |
|
GO:0003065 |
positive regulation of heart rate by epinephrine |
|
GO:0003779 |
actin binding |
|
GO:0005200 |
structural constituent of cytoskeleton |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005856 |
cytoskeleton |
|
GO:0005862 |
muscle thin filament tropomyosin |
|
GO:0006928 |
cellular component movement |
|
GO:0006936 |
muscle contraction |
|
GO:0006937 |
regulation of muscle contraction |
|
GO:0007010 |
cytoskeleton organization |
|
GO:0008016 |
regulation of heart contraction |
|
GO:0008307 |
structural constituent of muscle |
|
GO:0015629 |
actin cytoskeleton |
|
GO:0030017 |
sarcomere |
|
GO:0030049 |
muscle filament sliding |
|
GO:0030336 |
negative regulation of cell migration |
|
GO:0031529 |
ruffle organization |
|
GO:0032059 |
bleb |
|
GO:0032587 |
ruffle membrane |
|
GO:0032781 |
positive regulation of ATPase activity |
|
GO:0034614 |
cellular response to reactive oxygen species |
|
GO:0042060 |
wound healing |
|
GO:0045214 |
sarcomere organization |
|
GO:0045785 |
positive regulation of cell adhesion |
|
GO:0051496 |
positive regulation of stress fiber assembly |
|
GO:0055010 |
ventricular cardiac muscle tissue morphogenesis |
|
GO:0060048 |
cardiac muscle contraction |
