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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004945

Entrez Gene ID

7172

Official Gene Symbol

TPMT

Gene name

thiopurine S-methyltransferase

Gene Type

protein-coding

Chromosome

6

Genomics Location

6p22.3

Protein products

Thiopurine S-methyltransferase

Thiopurine S-methyltransferase

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Drug-induced hepatitis

Hepatocellular carcinoma

Primary biliary cirrhosis

Database cross reference

HGNC:12014
MIM:187680
Ensembl:ENSG00000137364
HPRD:01760
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005625

soluble fraction

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

GO:0006805

xenobiotic metabolic process

GO:0008119

thiopurine S-methyltransferase activity

GO:0008152

metabolic process

GO:0014070

response to organic cyclic compound

GO:0016740

transferase activity

GO:0032259

methylation

GO:0033574

response to testosterone stimulus

GO:0046498

S-adenosylhomocysteine metabolic process

GO:0046500

S-adenosylmethionine metabolic process