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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004946

Entrez Gene ID

7173

Official Gene Symbol

TPO

Synonyms

MSA|TDH2A|TPX

Gene name

thyroid peroxidase

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p25

Known cancer genes

Yes

Protein products

Thyroid peroxidase

Thyroid peroxidase

Thyroid peroxidase

Thyroid peroxidase

Putative uncharacterized protein TPO

TPO protein

Related liver disease name

Hepatitis C

Hepatocellular carcinoma

Database cross reference

HGNC:12015
MIM:606765
Ensembl:ENSG00000115705
HPRD:06000
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004447

iodide peroxidase activity

GO:0004601

peroxidase activity

GO:0005509

calcium ion binding

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006979

response to oxidative stress

GO:0009986

cell surface

GO:0016491

oxidoreductase activity

GO:0020037

heme binding

GO:0034641

cellular nitrogen compound metabolic process

GO:0042446

hormone biosynthetic process

GO:0042744

hydrogen peroxide catabolic process