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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004953

Entrez Gene ID

7181

Official Gene Symbol

NR2C1

Synonyms

TR2

Gene name

nuclear receptor subfamily 2, group C, member 1

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q22

Known cancer genes

Yes

Protein products

Nuclear receptor subfamily 2 group C member 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:7971
MIM:601529
Ensembl:ENSG00000120798
HPRD:03318
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003707

steroid hormone receptor activity

GO:0004872

receptor activity

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0006355

regulation of transcription, DNA-dependent

GO:0008270

zinc ion binding

GO:0010467

gene expression

GO:0016605

PML body

GO:0034339

regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

GO:0042803

protein homodimerization activity

GO:0042826

histone deacetylase binding

GO:0043401

steroid hormone mediated signaling pathway

GO:0043565

sequence-specific DNA binding

GO:0046872

metal ion binding