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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004978

Entrez Gene ID

7251

Official Gene Symbol

TSG101

Synonyms

TSG10|VPS23

Gene name

tumor susceptibility gene 101

Gene Type

protein-coding

Chromosome

11

Genomics Location

11p15

Known cancer genes

Yes

Protein products

Tumor susceptibility protein isoform 3

Tumor susceptibility gene 101 protein

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:15971
MIM:601387
Ensembl:ENSG00000074319
HPRD:03229
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001558

regulation of cell growth

GO:0003677

DNA binding

GO:0003714

transcription corepressor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005769

early endosome

GO:0005770

late endosome

GO:0005771

multivesicular body

GO:0005886

plasma membrane

GO:0006464

protein modification process

GO:0006513

protein monoubiquitination

GO:0007049

cell cycle

GO:0007050

cell cycle arrest

GO:0008285

negative regulation of cell proliferation

GO:0010008

endosome membrane

GO:0015031

protein transport

GO:0016044

cellular membrane organization

GO:0016197

endosome transport

GO:0030154

cell differentiation

GO:0030216

keratinocyte differentiation

GO:0030374

ligand-dependent nuclear receptor transcription coactivator activity

GO:0031625

ubiquitin protein ligase binding

GO:0031902

late endosome membrane

GO:0043130

ubiquitin binding

GO:0043162

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

GO:0044419

interspecies interaction between organisms

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0046755

non-lytic virus budding

GO:0048306

calcium-dependent protein binding

GO:0051301

cell division