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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004980

Entrez Gene ID

7253

Official Gene Symbol

TSHR

Synonyms

CHNG1|LGR3|MGC75129|hTSHRNI

Gene name

thyroid stimulating hormone receptor

Gene Type

protein-coding

Chromosome

14

Genomics Location

14q31

Known cancer genes

Yes

Protein products

TSHR protein

Thyroid stimulating hormone receptor

TSHR protein

Thyroid stimulating hormone receptor

Thyrotropin receptor

Related liver disease name

Viral hepatitis

Hepatitis C

Chronic hepatitis C

Hepatocellular carcinoma

Database cross reference

HGNC:12373
MIM:603372
Ensembl:ENSG00000165409
HPRD:04537
RefSeq Genomic nucleotide accession:AC_000057
RefSeq Genomic nucleotide gi:89161192

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004872

receptor activity

GO:0004996

thyroid-stimulating hormone receptor activity

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007187

G-protein signaling, coupled to cyclic nucleotide second messenger

GO:0007189

activation of adenylate cyclase activity by G-protein signaling pathway

GO:0007267

cell-cell signaling

GO:0008284

positive regulation of cell proliferation

GO:0008344

adult locomotory behavior

GO:0030183

B cell differentiation

GO:0040012

regulation of locomotion

GO:0040018

positive regulation of multicellular organism growth