Gene basic information
| LiverAtlas Gene ID |
HuLG005009 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TNFSF4 |
|
Synonyms |
CD134L|CD252|GP34|OXN40L|OX4OL|TXGP1 |
|
Gene name |
tumor necrosis factor (ligand) superfamily, member 4 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q25 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11934
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001816 |
cytokine production |
|
GO:0002215 |
defense response to nematode |
|
GO:0002526 |
acute inflammatory response |
|
GO:0002726 |
positive regulation of T cell cytokine production |
|
GO:0002819 |
regulation of adaptive immune response |
|
GO:0002830 |
positive regulation of type 2 immune response |
|
GO:0002891 |
positive regulation of immunoglobulin mediated immune response |
|
GO:0005102 |
receptor binding |
|
GO:0005125 |
cytokine activity |
|
GO:0005164 |
tumor necrosis factor receptor binding |
|
GO:0005615 |
extracellular space |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006955 |
immune response |
|
GO:0007165 |
signal transduction |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0009615 |
response to virus |
|
GO:0009986 |
cell surface |
|
GO:0016020 |
membrane |
|
GO:0032689 |
negative regulation of interferon-gamma production |
|
GO:0032700 |
negative regulation of interleukin-17 production |
|
GO:0032729 |
positive regulation of interferon-gamma production |
|
GO:0032733 |
positive regulation of interleukin-10 production |
|
GO:0032735 |
positive regulation of interleukin-12 production |
|
GO:0032736 |
positive regulation of interleukin-13 production |
|
GO:0032743 |
positive regulation of interleukin-2 production |
|
GO:0032753 |
positive regulation of interleukin-4 production |
|
GO:0032755 |
positive regulation of interleukin-6 production |
|
GO:0032813 |
tumor necrosis factor receptor superfamily binding |
|
GO:0035708 |
interleukin-4-dependent isotype switching to IgE isotypes |
|
GO:0035709 |
memory T cell activation |
|
GO:0035712 |
T-helper 2 cell activation |
|
GO:0042098 |
T cell proliferation |
|
GO:0042104 |
positive regulation of activated T cell proliferation |
|
GO:0042221 |
response to chemical stimulus |
|
GO:0043372 |
positive regulation of CD4-positive, alpha-beta T cell differentiation |
|
GO:0043382 |
positive regulation of memory T cell differentiation |
|
GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0045590 |
negative regulation of regulatory T cell differentiation |
|
GO:0045626 |
negative regulation of T-helper 1 cell differentiation |
|
GO:0045630 |
positive regulation of T-helper 2 cell differentiation |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0046641 |
positive regulation of alpha-beta T cell proliferation |
|
GO:0050710 |
negative regulation of cytokine secretion |
|
GO:0050727 |
regulation of inflammatory response |
|
GO:0050729 |
positive regulation of inflammatory response |
|
GO:0050871 |
positive regulation of B cell activation |
|
GO:0051024 |
positive regulation of immunoglobulin secretion |
|
GO:0071222 |
cellular response to lipopolysaccharide |
|
GO:0071380 |
cellular response to prostaglandin E stimulus |
|
GO:0071954 |
chemokine (C-C motif) ligand 11 production |
