HuLG005010

Entrez Gene ID

7293

Official Gene Symbol

TNFRSF4

Synonyms

ACT35|CD134|OX40|TXGP1L

Gene name

tumor necrosis factor receptor superfamily, member 4

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36

Known cancer genes

Yes

Protein products

Tumor necrosis factor receptor superfamily member 4

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:11918
MIM:600315
Ensembl:ENSG00000186827
HPRD:02636
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

GO annotation

GO:0004872

receptor activity

GO:0005031

tumor necrosis factor receptor activity

GO:0005488

binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006954

inflammatory response

GO:0006955

immune response

GO:0006968

cellular defense response

GO:0009897

external side of plasma membrane

GO:0009986

cell surface

GO:0030890

positive regulation of B cell proliferation

GO:0033209

tumor necrosis factor-mediated signaling pathway

GO:0042098

T cell proliferation

GO:0042981

regulation of apoptosis

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

GO:0045859

regulation of protein kinase activity

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0050710

negative regulation of cytokine secretion

GO:0051024

positive regulation of immunoglobulin secretion