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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005012

Entrez Gene ID

7295

Official Gene Symbol

TXN

Synonyms

DKFZp686B1993|MGC61975|TRX|TRX1

Gene name

thioredoxin

Gene Type

protein-coding

Chromosome

9

Genomics Location

9q31

Known cancer genes

Yes

Protein products

Thioredoxin

Related liver disease name

Hepatitis B

Hepatitis C

Chronic hepatitis C

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:12435
MIM:187700
Ensembl:ENSG00000136810
HPRD:01761
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0005829

cytosol

GO:0006355

regulation of transcription, DNA-dependent

GO:0006662

glycerol ether metabolic process

GO:0006810

transport

GO:0006928

cellular component movement

GO:0007165

signal transduction

GO:0007267

cell-cell signaling

GO:0008283

cell proliferation

GO:0009055

electron carrier activity

GO:0009314

response to radiation

GO:0015035

protein disulfide oxidoreductase activity

GO:0015037

peptide disulfide oxidoreductase activity

GO:0015949

nucleobase, nucleoside and nucleotide interconversion

GO:0022900

electron transport chain

GO:0033158

regulation of protein import into nucleus, translocation

GO:0043388

positive regulation of DNA binding

GO:0045454

cell redox homeostasis

GO:0046826

negative regulation of protein export from nucleus

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process

GO:0055114

oxidation-reduction process