Gene basic information
| LiverAtlas Gene ID |
HuLG005014 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TYK2 |
|
Synonyms |
JTK1 |
|
Gene name |
tyrosine kinase 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
19 |
|
Genomics Location |
19p13.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:12440
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0004713 |
protein tyrosine kinase activity |
|
GO:0004715 |
non-membrane spanning protein tyrosine kinase activity |
|
GO:0005131 |
growth hormone receptor binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005856 |
cytoskeleton |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007243 |
intracellular protein kinase cascade |
|
GO:0016020 |
membrane |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0060337 |
type I interferon-mediated signaling pathway |
|
GO:0060338 |
regulation of type I interferon-mediated signaling pathway |
